Protein Details: Probable cyclic nucleotide-gated ion channel 3

Protein ID

ICDB_Pro_1633

Protein Name

Probable cyclic nucleotide-gated ion channel 3

Gene Name

CNGC3 At2g46430 F11C10.12

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

706 amino acids

AlphaFoldDB

AF-Q9SKD7-F1-model_v4.pdb

Function

Probable cyclic nucleotide-gated ion channel.

Sequence

MMNPQRNKFVRFNGNDDEFSTKTTRPSVSSVMKTVRRSFEKGSEKIRTFKRPLSVHSNKNKENNKKKKILRVMNPNDSYLQSWNKIFLLLSVVALAFDPLFFYIPYVKPERFCLNLDKKLQTIACVFRTFIDAFYVVHMLFQFHTGFITPSSSGFGRGELNEKHKDIALRYLGSYFLIDLLSILPIPQVVVLAIVPRMRRPASLVAKELLKWVIFCQYVPRIARIYPLFKEVTRTSGLVTETAWAGAALNLFLYMLASHVFGSFWYLISIERKDRCWREACAKIQNCTHAYLYCSPTGEDNRLFLNGSCPLIDPEEITNSTVFNFGIFADALQSGVVESRDFPKKFFYCFWWGLRNLSALGQNLKTSAFEGEIIFAIVICISGLVLFALLIGNMQKYLQSTTVRVEEMRVKRRDAEQWMSHRMLPDDLRKRIRKYEQYKWQETKGVEEEALLSSLPKDLRKDIKRHLCLKLLKKVPWFQAMDDRLLDALCARLKTVLYTEKSYIVREGEPVEDMLFIMRGNLISTTTYGGRTGFFNSVDLVAGDFCGDLLTWALDPLSSQFPISSRTVQALTEVEGFLLSADDLKFVATQYRRLHSKQLRHMFRFYSVQWQTWAACFIQAAWKRHCRRKLSKALREEEGKLHNTLQNDDSGGNKLNLGAAIYASRFASHALRNLRANAAARNSRFPHMLTLLPQKPADPEFPMDET

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

BINDING 477..600; /ligand="a nucleoside 3,5-cyclic phosphate"; BINDING 548; /ligand="a nucleoside 3,5-cyclic phosphate"

Disease

Location

DOI ID

10.1046/j.1365-313x.1999.00422.x; 10.1038/45471; 10.1111/tpj.13415; 10.1126/science.1088305; 10.1104/pp.126.4.1646

RefSeq

NP_001118537.1; NP_566075.1